Calnomix as a Plant-Based Anti-Inflammatory Agent
Image 1. Calnomix Main Ingredients
Calnomix is a plant-based anti-inflammatory complex sourced from eco-friendly fields, forests, and mountains across Europe, Asia, and America. Specially designed for personal care formulations, it offers an inclusive skin-soothing and anti-irritation solution derived entirely from plants. Its primary components—Chamomile Extract, Portulaca Extract, and Maple Syrup Extract—are renowned for their ability to calm irritation, reduce inflammation, and enhance skin comfort.
By combining these botanical actives in a synergistic blend, Calnomix delivers dual anti-inflammatory and anti-irritation effects, making it a versatile choice for formulations targeting sensitive, reactive, or stressed skin.
How Calnomix Works
Image 2. Calnomix Summary Pathway
Calnomix works at the root of skin inflammation by targeting pro-inflammatory cytokines—specifically IL-1 and IL-6—both of which are critical markers in the skin’s inflammatory cascade.
Through modulation of the MAPK pathways (P38 and JNK), Calnomix helps reduce cytokine expression triggered by environmental stressors such as UVB exposure. This process restores skin balance and prevents chronic inflammation that can lead to redness, discomfort, and sensitivity.
This scientifically supported mechanism ensures that Calnomix not only soothes visible irritation but also supports long-term skin health.
Calnomix Benefits in Personal Care Formulations
Calnomix offers multiple benefits, validated by efficacy tests and safety studies, making it an excellent addition for brands seeking anti-inflammatory performance with natural origins:
Reduces inflammation
Significant reduction in IL-1 and IL-6 expression in UVB-exposed skin models.
Soothes irritation
Proven anti-irritation effect through controlled patch testing.
Moisturizes skin
Botanical extracts, especially Chamomile Extract and Portulaca Extract, contribute to hydration while calming skin.
Safe for sensitive skin
Clinical irritation test on 34 volunteers confirmed non-irritating after 24 hours, even at 10% concentration.
Eco-friendly origin
100% plant-based and sustainably sourced raw materials.
Efficacy Highlights:
- IL-1 Reduction: Calnomix showed measurable suppression of IL-1 levels, reducing inflammation at the cellular level.
Image 3. Reduction of Pro-Inflammatory Cytokine IL-1α Expression After UVB Exposure
- IL-6 Reduction: Similar reduction observed in IL-6 expression, further decreasing inflammatory responses.
Image 4. Reduction of Pro-Inflammatory Cytokine IL-6 Expression After UVB Exposure
- Non-Irritation Test: At a 10% concentration, Calnomix was proven safe with no irritation observed.
Image 5. 24-Hour Non-Irritation Result from Patch Test on 34 Participants (10% Calnomix)
Calnomix Applications in Personal Care
The gentle yet effective profile of Calnomix allows it to be incorporated into a wide variety of formulations, providing formulators with both performance and flexibility:
Skincare
Soothing creams, lotions, serums, and masks for sensitive or inflamed skin.
Haircare
Scalp-calming shampoos, conditioners, and leave-in treatments for irritated scalps.
Sensitive Skin Products
Baby care creams, post-sun gels, after-shave balms, and products for reactive skin types.
Recommended Dosage: 2–3% in the final formulation.
Calnomix Distributor
As a trusted Calnomix distributor, Maha provides technical support and formulation guidance to help you unlock the full Calnomix benefits in your products.
Incorporating Calnomix into your formulation enables you to deliver high-performance plant-based anti-inflammatory and anti-irritation products that meet consumer demand for natural, sustainable skincare.
Contact Maha today to consult directly with our experts and request your FREE Calnomix sample for trial in your next formulation.