γ-Polyglutamic Acid: Advanced Moisturizing Ingredient for Modern Formulations

14 August 2025

Moisturizing Agent for Long-Lasting Skin Hydration

In the fast-paced personal care market, consumers are seeking moisturizing agents that deliver not only instant hydration but also prolonged moisture retention. γ-Polyglutamic Acid (γ-PGA) is emerging as a next-generation ingredient that fulfills these demands.

Unlike conventional humectants, γ-PGA forms a breathable film on the skin, helping lock in moisture for hours while supporting the skin’s natural barrier. This makes it a powerful choice for brands developing moisturizers with polyglutamic acid or looking for hyaluronic acid alternatives.

PGA vs Hyaluronic Acid: Which Delivers Better Hydration?

Image 1. Polyglutamic Acid vs. Hyaluronic Acid

While Hyaluronic Acid (HA) is well-known for binding water molecules, γ-PGA offers a different mechanism of action. Studies show γ-PGA can retain moisture up to five times more effectively than HA, thanks to its film-forming ability and high water-binding capacity. Additionally, γ-PGA supports the skin’s natural production of Natural Moisturizing Factors (NMFs), making it not just a temporary hydrator but also a contributor to long-term skin health.

γ-Polyglutamic Acid: The Science Behind PGA

γ-PGA is a naturally derived biopolymer produced through the fermentation of Bacillus subtilis. Its structure consists of D- and L-glutamic acid units connected via gamma-amide bonds, giving it exceptional hydrophilicity and viscosity.

In skincare, these properties translate into:

  • Superior moisture retention through strong hydrogen bonding with water molecules.
  • Film-forming protection that reduces transepidermal water loss (TEWL).
  • Inhibition of melanin biosynthesis for a brighter, more even skin tone.
  • Biodegradability and skin compatibility, making it ideal for clean beauty formulations.

γ-Polyglutamic Acid Benefits for Personal Care Products

Formulators can leverage γ-PGA to deliver multiple benefits in one ingredient:

  • Enhanced and prolonged hydration for up to 12–24 hours.
  • Improved skin elasticity through increased NMF synthesis.
  • Skin brightening support via melanin biosynthesis inhibition.
  • Boosted efficacy of other actives, such as Vitamin C or peptides, by preventing rapid evaporation.
  • Non-irritating profile, suitable for sensitive skin products.

Its versatility allows γ-PGA to be incorporated in serums, creams, sheet masks, sunscreens, and even color cosmetics for an extra hydration boost.

γ-Polyglutamic Acid Applications in Cosmetic Formulations

γ-PGA can be formulated into various personal care and cosmetic products, including:

  • Facial moisturizers for deep hydration.
  • Anti-aging serums targeting fine lines and dryness.
  • Sheet masks for intensive moisture infusion.
  • Sunscreens to counteract UV-induced dryness.
  • Makeup products like foundations or primers for smoother application.

It is also compatible with other hydrating agents, antioxidants, and brightening ingredients, making it an excellent addition to multi-functional skincare.

γ-Polyglutamic Acid Serum Formulation Guide

γ-PGA serum is experiencing rising demand in the skincare market due to its ability to deliver intense hydration, improve skin elasticity, and reduce the appearance of fine lines. γ-PGA forms a moisture-retaining film, strengthens the skin barrier, and provides long-lasting hydration with a lightweight, non-greasy feel suitable for all skin types. It also works synergistically with actives like hyaluronic acid, niacinamide, and antioxidants for enhanced skincare performance.  

γ-PGA’s unique properties make it a powerful ingredient for innovative skincare formulations that meet the growing demand for effective hydration. Contact Maha at sales@maha.asia for expert guidance and a complete γ-PGA serum formulation guide to help you develop high-performance, market-ready products.

γ-Polyglutamic Acid Supplier

Maha offers γ-PGA produced through advanced fermentation processes and tested for high purity, ensuring optimal performance in personal care applications.

Experience the proven moisturizing power of γ-PGA! Contact Maha today to request technical guides, efficacy test results, and FREE samples for your next formulation.


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